@ScienceO
Science News
Science News
Followers:
25
The road to CAR-T-cell therapy for lethal childhood brain tumours
A phase I clinical trial of GD2-CAR T cells (immune cells engineered to target the molecule GD2) in children and young adults with diffuse midline gliomas — incurable cancers of the central nervous system — shows promising results. Several trial participants exhibited substantial improvements, and one child’s tumour has been undetectable for more than three years.
A mutation makes plant roots more welcoming to beneficial microbes
Promoting mutually beneficial relationships between plants and soil microbes that enhance nutrient acquisition by plants could improve crop production without increasing inorganic-fertilizer use. A mutation that causes an amino-acid substitution in a channel called CNGC15 in the plant cell’s nucleus boosts the formation of such endosymbiotic relationships.
Striving for open-source and equitable speech-to-speech translation
US technology company Meta has produced an AI model that can directly translate speech in one language to speech in another. Two scientists discuss the technical feats and ethical questions that underpin this advance in machine translation.